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LY-2584702 tosylate salt CAS: 1082949-68-5

Category: Inhibitors
Product Name: LY-2584702 tosylate salt
Cat No: I000362
CAS No: 1082949-68-5
Synonyms: LYS6K2
Molecular Formula: C21H19F4N7 • C7H8O3S
Molecular Weight: 617.6
SMILES: FC(C(C(F)(F)F)=C1)=CC=C1C2=CN(C)C(C3CCN(C4=C(C=NN5)C5=NC=N4)CC3)=N2.CC6=CC=C(S(=O)(O)=O)C=C6
InChI: None
InChIKey: HDYUXDNMHBQKAU-UHFFFAOYSA-N
Solubility: DMSO: ≤ 10.25 mg/mL
Target: p70S6K inhibitor
Storage: -20°C
CAS 1082949-68-5,LY-2584702 tosylate salt
  • Description

LY-2584702 tosylate salt is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
IC50 value:
Target: p70S6K inhibitor
LY-2584702 is an orally available inhibitor of p70S6K signaling, with potential antineoplastic activity. LY2584702 inhibits ribosomal protein S6 Kinase (p70S6K), and prevents phosphorylation of the S6 subunit of ribosomes, thereby inhibiting normal ribosomal function within tumor cells leading to a decrease in protein synthesis and in cellular proliferation. P70S6K, a serine/threonine kinase, acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway, is often upregulated in a variety of cancer cells, and is involved in the regulation of cell growth, proliferation, motility, and survival.

  • Spec

Appearance:White to off-white solid powder
Purity: > 98%

  • References


price inquiry for CAS:1082949-68-5, Product:LY-2584702 tosylate salt