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A-841720 CAS: 869802-58-4

Category: Inhibitors
Product Name: A-841720
Cat No: I000318
CAS No: 869802-58-4
Synonyms: A-841720;9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one
Molecular Formula: C17H21N5OS
Molecular Weight: 343.45
InChI: InChI=1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
Solubility: Soluble in DMSO
Target: GluR
Storage: Store at RT
CAS 869802-58-4,A-841720
  • Description

A-841720 is a metabotropic glutamate receptor 1 antagonist.

  • Spec

Appearance:Solid powder
Purity: > 98%

  • References

1:Comparison of the mGluR1 antagonist A-841720 in rat models of pain and cognition. Morè L, Gravius A, Pietraszek M, Belozertseva I, Malyshkin A, Shekunova E, Barberi C, Schaefer D, Schmidt WJ, Danysz W.Behav Pharmacol. 2007 Jul;18(4):273-81. PMID: 17551319
2:Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist. El-Kouhen O, Lehto SG, Pan JB, Chang R, Baker SJ, Zhong C, Hollingsworth PR, Mikusa JP, Cronin EA, Chu KL, McGaraughty SP, Uchic ME, Miller LN, Rodell NM, Patel M, Bhatia P, Mezler M, Kolasa T, Zheng GZ, Fox GB, Stewart AO, Decker MW, Moreland RB, Brioni JD, Honore P.Br J Pharmacol. 2006 Nov;149(6):761-74. Epub 2006 Oct 3. PMID: 17016515 Free PMC Article

price inquiry for CAS:869802-58-4, Product:A-841720