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A-794282 CAS: 869802-44-8

Category: Inhibitors
Product Name: A-794282
Cat No: I000300
CAS No: 869802-44-8
Synonyms: A-794282;13-(dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular Formula: C19H18N4OS
Molecular Weight: 350.44
SMILES: O=C1N(C2=CC=C(CC)C=C2)C=NC3=C1SC4=NC=CC(N(C)C)=C34
InChI: InChI=1S/C19H18N4OS/c1-4-12-5-7-13(8-6-12)23-11-21-16-15-14(22(2)3)9-10-20-18(15)25-17(16)19(23)24/h5-11H,4H2,1-3H3
InChIKey: VCUKKMIXURRDKL-UHFFFAOYSA-N
Solubility: Soluble in DMSO
Target: selective mGluR1 antagonist.
Storage: 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
CAS 869802-44-8,A-794282
  • Description

A-794282 is a selective mGluR1 antagonist.

  • Spec

Appearance:Solid powder
Purity: > 98%

  • References


1: Yang YL, Sun W, Peng C, Zhang XY, Yang XH. [Research progress of selective mGluR1 antagonists]. Yao Xue Xue Bao. 2011 Oct;46(10):1167-72. Review. Chinese. PubMed PMID: 22242445.
2: Zhu CZ, Baker S, EI-Kouhen O, Lehto SG, Hollingsworth PR, Gauvin DM, Hernandez G, Zheng G, Chang R, Moreland RB, Stewart AO, Brioni JD, Honore P. Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats. Eur J Pharmacol. 2008 Feb 12;580(3):314-21. PubMed PMID: 18054908.
3: Zheng GZ, Bhatia P, Daanen J, Kolasa T, Patel M, Latshaw S, El Kouhen OF, Chang R, Uchic ME, Miller L, Nakane M, Lehto SG, Honore MP, Moreland RB, Brioni JD, Stewart AO. Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists. J Med Chem. 2005 Nov 17;48(23):7374-88. PubMed PMID: 16279797.


price inquiry for CAS:869802-44-8, Product:A-794282