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A61603 CAS: 750531-54-5

Category: Inhibitors
Product Name: A61603
Cat No: I000288
CAS No: 750531-54-5
Synonyms: A61603;N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide
Molecular Formula: C14H19N3O3S
Molecular Weight: 309.384
SMILES: CS(=O)(NC1=C2CCCC(C3=NCCN3)C2=CC=C1O)=O
InChI: InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)
InChIKey: OQFCXJDXHCDLHX-UHFFFAOYSA-N
Solubility: Soluble in DMSO
CAS 750531-54-5,A61603
  • Description

A61603(cas 750531-54-5) is a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype. 

  • Spec

Appearance:Solid powder
Purity: > 98%

  • References

1: Mehrotra S, Gupta S, Centurión D, Villalón CM, Saxena PR, VandenBrink AM. A61603-induced contractions of the porcine meningeal artery are mediated by alpha1- and alpha2-adrenoceptors. Basic Clin Pharmacol Toxicol. 2007 Apr;100(4):279-85. PubMed PMID: 17371533.
2: Willems EW, Heiligers JP, De Vries P, Tom B, Kapoor K, Villalón CM, Saxena PR. A61603-induced vasoconstriction in porcine carotid vasculature: involvement of a non-adrenergic mechanism. Eur J Pharmacol. 2001 Apr 13;417(3):195-201. PubMed PMID: 11334851.


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