Home> Products> Inhibitors> ARN2966-CAS 102212-26-0
price inquiry for CAS:102212-26-0, Product:ARN2966
For research use only. We do not sell to patients.

ARN2966 CAS: 102212-26-0

Category: Inhibitors
Product Name: ARN2966
Cat No: I000154
CAS No: 102212-26-0
Synonyms: 2-((pyridin-2-ylmethyl)amino)phenol
Molecular Formula: C12H12N2O
Molecular Weight: 200.2
Solubility: DMSO: ≥ 43.4 mg/mL
Target: Amyloid β
Storage: Desiccate at -20°C
CAS 102212-26-0,ARN2966
  • Description

ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.
IC50 value:
Target: Aβ
This potent post-transcriptional modulation of APP expression differs from other mechanisms such as inhibition of secretases. Secretase inhibitors have been pursued as disease modifying strategies by a number of pharmaceutical firms but they have encountered numerous setbacks during clinical development. ARN2966 is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo.

  • Spec


  • References

[1]. http://arianeurosciences.com/science.html

price inquiry for CAS:102212-26-0, Product:ARN2966