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Tyrosine kinase inhibitor CAS: 1021950-26-4

Category: Inhibitors
Product Name: Tyrosine kinase inhibitor
Cat No: I000153
CAS No: 1021950-26-4
Synonyms: N-(4-fluorophenyl)-N-(4-((2-((2-morpholinoethyl)carbamoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide
Molecular Formula: C31H31FN6O5
Molecular Weight: 586.6
SMILES: O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC(C=C3)=CC=C3OC4=C5C(NC(C(NCCN6CCOCC6)=O)=C5)=NC=C4
InChIKey: PKOVTRMHYNEBDU-UHFFFAOYSA-N
Solubility: DMSO: ≥ 46 mg/mL
Target: c-MET
Storage: Store at -20°C
CAS 1021950-26-4,Tyrosine kinase inhibitor
  • Description

A Tyrosine kinase inhibitor.

  • Spec

None

  • References


[1]. Inoue T, Kinoshita H, Komai Y, Kawabata T, Kawa G, Uemura Y, Matsuda T. Two cases of gastrointestinal perforation after radiotherapy in patients receiving tyrosine kinase inhibitor for advanced renal cell carcinoma. World J Surg Oncol. 2012 Aug 20;10(1):167.
[2]. Bowen JM, Mayo BJ, Plews E, Bateman E, Stringer AM, Boyle FM, Finnie JW, Keefe DM. Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea. Cancer Biol Ther. 2012 Nov 1;13(13).
[3]. Sun FK, He HC, Su TW, Zhou WL, Huang X, Dai J, Shen ZJ. Multi-targeted tyrosine kinase inhibitor sunitinib: a novel strategy for sporadic malignant pheochromocytoma. Chin Med J (Engl). 2012 Jun;125(12):2231-4.
[4]. Thamm DH. Tyrosine kinase inhibitor special issue. Vet Comp Oncol. 2012 Sep;10(3):161-2. doi: 10.1111/j.1476-5829.2012.00339.x.
[5]. Eriksson A, Hermanson M, Wickstr?m M, Lindhagen E, Ekholm C, Jenmalm Jensen A, L?thgren A, Lehmann F, Larsson R, Parrow V, H?glund M. The novel tyrosine kinase inhibitor AKN-028 has significant antileukemic activity in cell lines and primary cultures of acute myeloid leukemia. Blood Cancer J. 2012 Aug 3;2:e81. doi: 10.1038/bcj.2012.28.


price inquiry for CAS:1021950-26-4, Product:Tyrosine kinase inhibitor