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A-119637 CAS: 255713-47-4

Category: Inhibitors
Product Name: A-119637
Cat No: I000134
CAS No: 255713-47-4
Synonyms: A-119637;3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5-phenyl-1H-thieno[3,2-e]pyrimidine-2,4-dione
Molecular Formula: C25H26N4O3S
Molecular Weight: 462.568
SMILES: O=C1N(CCN2CCN(C3=CC=CC=C3OC)CC2)C(C(C(C4=CC=CC=C4)=CS5)=C5N1)=O
InChI: InChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31)
InChIKey: HLVQBOYEHQRWHG-UHFFFAOYSA-N
Solubility: Soluble in DMSO
Target: alpha1D antagonist
CAS 255713-47-4,A-119637
  • Description

A-119637(cas 255713-47-4) is a novel, selective and potent alpha1D antagonist.

  • Spec

Appearance:Solid powder
Purity: > 98%

  • References

1: Mizusawa H, Hedlund P, Sjunnesson J, Brioni JD, Sullivan JP, Andersson KE. Enhancement of apomorphine-induced penile erection in the rat by a selective alpha(1D)-adrenoceptor antagonist. Br J Pharmacol. 2002 Jul;136(5):701-8. PubMed PMID: 12086979; PubMed Central PMCID: PMC1573401.
2: Carroll WA, Sippy KB, Esbenshade TA, Buckner SA, Hancock AA, Meyer MD. Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien. Bioorg Med Chem Lett. 2001 May 7;11(9):1119-21. PubMed PMID: 11354357.


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