LPA2 antagonist 1

CAS No. : 1017606-66-4

LPA2 antagonist 1,1017606-66-4
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000131
Molecular Formula:C20H23Cl2N5O2S2
Molecular Weight:500.5
Target:LPL Receptor
IC50:> 30 uM [1]
Price:Get quote
We match the lowest price on market.

Your information is safe with us.

Appearance:Solid powder
Purity: > 98%
Cat No:I000131
Cas No:1017606-66-4
Product-Name:LPA2 antagonist 1

LPA2 antagonist1 is a selective inhibitor of LPA2 activity in with IC50 17 nM in vitro for inhibition of LPA(2) mediated Erk activation and proliferation of HCT-116 cells.
IC50 value: > 30 uM [1]
Target: LPA2

[1]. Beck HP, et al. Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1037-41.
[2]. Kozian DH, et al. Selective non-lipid modulator of LPA5 activity in human platelets. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5239-43.

Recommended Products
  • CAS No. :163210-43-3
    Product Name:

    4-Allyloxy-piperidine-1-carboxylic acid tert-butyl ester

    Cat No: M036489 View details
  • CAS No. :192182-56-2
    Product Name:

    4-Isoquinolineboronic acid

    Cat No: M036491 View details
  • CAS No. :185318-74-5
    Product Name:


    Cat No: M036492 View details
  • CAS No. :192433-20-8
    Product Name:

    Cyclohexanecarboxylic acid, 1-methyl-3-oxo-, (R)- (9CI)

    Cat No: M036493 View details