CAS No. : 10083-24-6

Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000099
Molecular Formula:C₁₄H₁₂O₄
Molecular Weight:244.24
Price:Get quote
We match the lowest price on market.

Your information is safe with us.

Appearance: Powder
Purity: 98.5%
Cat No:I000099
Cas No:10083-24-6
MDL No:MFCD00221715

Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects.
In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppressed in lymphocyte and epithelial cells. Piceatannol also inhibited NF-κB activated by H2O2, PMA, LPS, okadaic acid, and ceramide. [1]

[1]. Kazuhiro Ashikawa et al. Piceatannol Inhibits TNF-Induced NF-κB Activation and NF-κB-Mediated Gene Expression Through Suppression of IκBα Kinase and p65 Phosphorylation. J Immunol, 2002 Dec 1, 169(11):6490-7.
[2]. Wen-Pin Chen et al. Piceatannol, a derivative of resveratrol, moderately slows INa inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts. Br J Pharmacol.2009 Jun, 157(3), 381-391.

Related Products
  • CAS No. :862812-98-4
    Product Name:

    IKK-3 Inhibitor

    Cat No: I005172 View details
  • CAS No. :5508-58-7
    Product Name:


    Cat No: I004042 View details
  • CAS No. :873225-46-8
    Product Name:

    IKK 16

    Cat No: I005258 View details
  • CAS No. :524-12-9
    Product Name:


    Cat No: R006650 View details