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T-705 CAS: 259793-96-9

Category: Inhibitors
Product Name: T-705
Cat No: I000017
CAS No: 259793-96-9
Related CAS: I000017
Synonyms: Favipiravir
Molecular Formula: C5H4FN3O2
Molecular Weight: 157.1
MDL No: MFCD12032148
InChI: InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
Solubility: >6.2mg/mL in DMSO
Target: HCV
Storage: Store at -20°C
CAS 259793-96-9,T-705
  • Description

Favipiravir(cas 259793-96-9), also known as T-705 or Avigan, is an antiviral drug that selectively inhibits the RNA-dependent RNA polymerase of influenza virus. It is phosphoribosylated by cellular enzymes to its active form, favipiravir-ribofuranosyl-5'-triphosphate (RTP).  Favipiravir is active against a broad range of influenza viruses, including A(H1N1)pdm09, A(H5N1) and the recently emerged A(H7N9) avian virus. It also inhibits influenza strains resistant to current antiviral drugs, and shows a synergistic effect in combination with oseltamivir, thereby expanding influenza treatment options.

  • Spec

Appearance:Solid powder
Purity: > 98%

  • References

1: Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013 Nov;100(2):446-54. doi: 10.1016/j.antiviral.2013.09.015. Epub 2013 Sep 29. Review. PubMed PMID: 24084488; PubMed Central PMCID: PMC3880838.
2: Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD. T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res. 2009 Jun;82(3):95-102. doi: 10.1016/j.antiviral.2009.02.198. Epub 2009 Mar 6. Review. PubMed PMID: 19428599.

price inquiry for CAS:259793-96-9, Product:T-705